2015年度
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- Amino acids, 47(8), 1579-87, 2015.
Identification of a novel amino acid racemase from a hyperthermophilic archaeon Pyrococcus horikoshii OT-3 induced by D-amino acids.
K. Kawakami, T. Ohmori, H. Sakuraba, T. Ohshima
- 生化学, .
耐熱性D-アミノ酸脱水素酵素のタンパク質工学的創製と利用、
秋田紘長, 大島敏久, 櫻庭春彦
- Appl. Microbiol. Biotechnol. 99. In press
Dye-linked D-amino acid dehydrogenase from the thermophilic bacterium Rhodothermus marinus JCM 9785: characteristics and role in trans-4-hydroxy-L-proline catabolism.
T. Satomura, H. Sakuraba, S. Suye, T. Ohshima
- Biosci. Biotechnol. Biochem. in press
FumioFunctional and Structural Characteristics of Methylmalonyl-CoA Mutase from Pyrococcus horikoshii.
Y.Yabuta, Y. Kamei,T. Bito, J. Arima, K. Yoneda,H. Sakuraba, T. Ohshima, Y. Nakano, F. Watanabe
- Biotechnol. Lett. 36, 2245-2248.
Spectrophotometric assay of D-isoleucine using an artificially created D-amino acid dehydrogenase,
H. Akita, Y. Imaizumi, H. Suzuki, K. Doi, T. Ohshima
- Acta Crystallogr F Struct Biol Commun. 70: 890-895.
Structure of D-tagatose 3-epimerase-like protein from Methanocaldococcus jannaschii.
K. Uechi, G. Takata, K.Yoneda, T. Ohshima, H. Sakuraba.
- bio-prptpcol 4, Iss17, 3 pages (http://bio-protocol.org/e1231).
Analysis of L- and D-amino acid using UPLC,
Y. Mutaguchi, T. Ohmori, T. Ohshima
- Enzyme and Mirobial Technology 60, 40-46.
Biochemical characterization of an L-tryptophan dehydrogenase from the photoautotrophic cyanobacterium Nostoc punctiforme,
R. Ogura, T. Wakamatsu, K. Doi, T. Ohshima
- Acta Crystallogr. D, Biol. Crystallogr. 70, 1271-1280.
Structural insight into glucose dehydrogenase from the thermoacidophilic archaeon Thermoplasma volcanium.
Y. Kanoh, S. Uehara, H. Iwatani, T. Ohshima, H. Sakuraba
- 朝倉書店 pp.217-218.
環境と微生物の事典 第5章極限環境の微生物、地熱発電所と微生物、
土居克実、大島敏久
- Appl Microbiol Biotechnol. 98:1135-1143 .
Efficient synthesis of D-branched-chain amino acids and their labeled compounds with stable isotopes using D-amino acid dehydrogenase.
H. Akita, H. Suzuki, K. Doi, T. Ohshima
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2014年度
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- Biosci Biotechnol Biochem. Epub ahead of print(6 pages).
Identification of catalytic residues of a very large NAD-glutamate dehydrogenase from Janthinobacterium lividum by site-directed mutagenesis.
K. Kawakami, H. Sakuraba, T. Ohshima
- 化学と生物, 53 (1), 18-26, 2015.
乳酸菌とD-アミノ酸生産、
牟田口祐太, 大森勇門，大島敏久
- Appl. Microbiol. Biotechnol. 99. In press
Dye-linked D-amino acid dehydrogenase from the thermophilic bacterium Rhodothermus marinus JCM 9785: characteristics and role in trans-4-hydroxy-L-proline catabolism.
T. Satomura, H. Sakuraba, S. Suye, T. Ohshima
- Biosci. Biotechnol. Biochem. in press
FumioFunctional and Structural Characteristics of Methylmalonyl-CoA Mutase from Pyrococcus horikoshii.
Y.Yabuta, Y. Kamei,T. Bito, J. Arima, K. Yoneda,H. Sakuraba, T. Ohshima, Y. Nakano, F. Watanabe
- Biotechnol. Lett. 36, 2245-2248.
Spectrophotometric assay of D-isoleucine using an artificially created D-amino acid dehydrogenase,
H. Akita, Y. Imaizumi, H. Suzuki, K. Doi, T. Ohshima
- Acta Crystallogr F Struct Biol Commun. 70: 890-895.
Structure of D-tagatose 3-epimerase-like protein from Methanocaldococcus jannaschii.
K. Uechi, G. Takata, K.Yoneda, T. Ohshima, H. Sakuraba.
- bio-prptpcol 4, Iss17, 3 pages (http://bio-protocol.org/e1231).
Analysis of L- and D-amino acid using UPLC,
Y. Mutaguchi, T. Ohmori, T. Ohshima
- Enzyme and Mirobial Technology 60, 40-46.
Biochemical characterization of an L-tryptophan dehydrogenase from the photoautotrophic cyanobacterium Nostoc punctiforme,
R. Ogura, T. Wakamatsu, K. Doi, T. Ohshima
- Acta Crystallogr. D, Biol. Crystallogr. 70, 1271-1280.
Structural insight into glucose dehydrogenase from the thermoacidophilic archaeon Thermoplasma volcanium.
Y. Kanoh, S. Uehara, H. Iwatani, T. Ohshima, H. Sakuraba
- 朝倉書店 pp.217-218.
環境と微生物の事典 第5章極限環境の微生物、地熱発電所と微生物、
土居克実、大島敏久
- Appl Microbiol Biotechnol. 98:1135-1143 .
Efficient synthesis of D-branched-chain amino acids and their labeled compounds with stable isotopes using D-amino acid dehydrogenase.
H. Akita, H. Suzuki, K. Doi, T. Ohshima
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2013年度
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- バイオインダストリー 8, 3-11.
超好熱菌の極限酵素の耐熱機構と応用,
櫻庭春彦, 大島敏久
- Springer, pp. 395-412
Thermophiles in Environmental and Industrial Biotechnology, Thermophiles in Industrial Biotechnology, Chapter 34: Thermophiles in Industrial Biotechnology,
Chapter 34: Heterogeneous Production of Thermostable Proteins and Enzymes,
H. Sakuraba、T. Ohshima
- Springerplus. 2:691 Open access.
Distribution of D-amino acids in vinegars and involvement of lactic acid bacteria in the production of D-amino acids.
Mutaguchi Y, Ohmori T, Akano H, Doi K, Ohshima T.
- J Bacteriol. 195(22):5207-15.
Identification, purification, and characterization of a novel amino acid racemase, isoleucine 2-epimerase, from Lactobacillus species.
Mutaguchi Y, Ohmori T, Wakamatsu T, Doi K, Ohshima T.
- 農芸化学会中四国支部第16回若手シンポジウム招待講演、
発酵食品に含まれるアミノ酸の研究、
大森勇門、牟田口祐太、守﨑香菜、土居克実、大島敏久
- Genome Announc. 1(4) Open access.
Draft Genome Sequence of D-Branched-Chain Amino Acid Producer Lactobacillus otakiensis JCM 15040T, Isolated from a Traditional Japanese Pickle.
Doi K, Mori K, Mutaguchi Y, Tashiro K, Fujino Y, Ohmori T, Kuhara S, Ohshima T.
- Extremophiles. 17(3):379-89.
Biochemical characterization of two glutamate dehydrogenases with different cofactor specificities from a hyperthermophilic archaeon Pyrobaculum calidifontis.
Wakamatsu T, Higashi C, Ohmori T, Doi K, Ohshima T.
- Genome Announc. 1. e00156-12.
Draft Genome Sequence of Pediococcus lolii NGRI 0510Q(T) Isolated from Ryegrass Silage.
K. Doi, K. Mori, K. Tashiro, Y. Fujino, Y. Nagayoshi, Y. Hayashi, S. Kuhara, T. Ohshima
- Appl. Environ. Microbiol. 79, 5151-5158.
Polysaccharide- Degrading Thermophiles Generated by Heterologous Gene Expression in Geobacillus kaustophilus HTA426,
H. Suzuki, K. Yoshida, T. Ohshima
- Biosci. Biotechnol. Biochem. 77, 2316-2318.
Ternary conjugation system to construct DNA libraries in Geobacillus kaustophilus HTA426,
H．Suzuki, K.Wada, M.Furukawa, K. Doi, T. Ohshima
- Advances in Microbiology, 3, 265-272.
Identification and Characterization of Lactic Acid Bacteria Isolated from Fermented Rice Bran Product.
K. Doi, Ong Thi Ahn Phuong, F. Kawatou, Y. Nagayoshi, Y. Fujino, T. Ohshima
- J. Molecul. Catalysis B: Enzymatic 94, 15-22.
Characterization of D-amino acid aminotransferase from Lactobacillus salivarius,
J. Kobayashi Y. Shimizu, K. Doi, T. Ohshima
- Acta Crystallogr. Sect F69, 134-136.
Crystallization and preliminary X-ray analysis of L-serine 3-dehydrogenase complexed with NADP+ from the hyperthermophili carchaeon Pyrobaculum calidifontis.
K. Yoneda, H. Sakuraba, T. Araki, T. Shibata, T. Nikki, T. Ohshima.
- Appl. Microbiol. Biotechnol., 97, 3419-3427.
Comparative analysis of the catalytic components in the archaeal dye-linked L-proline dehydrogenase complexes,
R. Kawakami, C. Noguchi, M. Higashi, H. Sakuraba, Ohshima T.
- Biosci. Biotechnol. Biochem. 77(4):847-9.
Increased Tyrosine in the Brain and Serum of Mice by Orally Administering Dipeptide SY.
Esaki K, Ohmori T, Maebuchi M, Nakamori T, Ohshima T, Furuya S.
- 生化学 アトモスフィア 85、831 (巻頭言)
「科学技術創造立国」日本では博士号取得者がもっと生かされるべきでは.
大島敏久
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2012年度
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- J. Molecul. Catal. B: Enzymatic 83,65-72.
A psychrophilic leucine dehydrogenase from Sporosarcina psychrophila: purification, characterization, gene sequencing and crystal structure analysis.
Y. Zhau, T. Wakamatsu, H.Sakuraba, K. Doi, T. Ohshima
- Bicsci. Biotechnol. Biochem. 76:1601-1610.
Structural characteristics of active and inactive glutamate dehydrogenase from Pyrobaculum islandicum,
T. Ohshima
- Biotechnol. Lett. 34,1693－1699.
Creation of a thermostable NADP+-dependent D-amino acid dehydrogenase from Ureibacillus thermosphaericus strain
A1 meso-diaminopimelate dehydrogenase by site-directed mutagenesis,
H. Akita, K. Doi, Y. Kawarabayasi, T. Ohshima
- Appl. Microbiol. Biotechnol. 95,707-716.
Expression analysis of the spi gene in the pock-forming plasmid pSA1.1 from Streptomyces azureus and localization of its product during differentiation.
K. Doi,Y. Ohyama, E.Yokoyama, T. Nishiyama, Y.Fujino, Y Nagayoshi, T. Ohshima, S. Ogata
- J. Biosci. Bioeng. 114(4):457-9.
Effects of alkali or acid treatment on the isomerization of amino acids.
T. Ohmori, Y. Mutaguchi, K. Doi, T. Ohshima.
- J. Biol. Chem. 287, 20070-20080.
Crystal Structure of Novel Dye-linked L-Proline Dehydrogenase from Hyperthermophilic Archaeon Aeropyrum pernix.
H. Sakuraba, T. Satomura, R. Kawakami, K. Kim, Y. Hara, K. Yoneda, T. Ohshima
- The Journal of Poultry Science. Open access.
Oral administration of D-aspartate, but not of L-aspartate, reduces food intake in chicks.
E. Erwan, S. Tomonaga, T. Ohmori, Y. Mutaguchi , T.Ohshima, M. Nagasawa, S. Yasuo, Y. Tamura and M.Furuse
- Biosci. Biotechnol. Biochem. 76, 589-593.
Gene expression and characterization of a third type of dye-linked L-proline dehydrogenase from the aerobic hyperthermophilic archaeon, Aeropyrum pernix.
T. Satomura, Y. Hara, S. Suye, H. Sakuraba Sakuraba H, T. Ohshima.
- Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 68(Pt 3), 330-332.
Expression, purification, crystallization and preliminary X-ray diffraction analysis of a galactose 1-phosphate uridylyltransferase
from the hyperthermophilic archaeon Pyrobaculum aerophilum.
T. Satomura, A. Hiraki, T. Kawai, R. Kawakami, T. Ohshima, H. Sakuraba.
- J. Biol. Chem. 287, 12966-12974.
Crystal structure of binary and ternary complexes of archaeal UDP-galactose 4-epimerase-like L-threonine dehydrogenase from Thermoplasma volcanium.
K.Yoneda, H. Sakuraba, T. Araki, T. Ohshima
- Appl.Microbiol. Biotechnol. 93, 83-93.
L-proline dehydrogenases in hyperthermophilic archaea: distribution, function, structure, and application,
R. Kawakami, T. Satomura, H. Sakuraba, T. Ohshima
- Acta Crystallogr Sect F Struct Biol Cryst Commun. 67(Pt 11),1425-1427.
Crystallization and preliminary X-ray analysis of a dye-linked D-lactate dehydrogenase from the aerobic hyperthermophilic archaeon Aeropyrum pernix.
T. Shibahara, T. Satomura, R. Kawakami, T. Ohshima, H. Sakuraba
- ＣＭＣ出版 153-159.
「極限環境生物の産業展開」 高温バイオプロセス開発のための好熱菌宿主の開発、
鈴木宏和、大島敏久
- 日本農芸化学会西日本支部若手シンポジウム招待講演、
食品機能成分としてのD-アミノ酸の可能性、
大森勇門、牟田口祐太、守﨑香菜、土居克実、大島敏久
- 化学同人、ひらく、ひらく「バイオの世界」、
日本生物工学会編 執筆者75名のうちの2名(大島敏久、大森勇門)として執筆
- 酵素工学ニュース67、20-24.
好熱性シアノバクテリア由来Photosystem Iの安定化技術の開発と太陽電池への応用.
松本和也、大島敏久
- バイオインダストリー、70, 340-345.
フラビン含有色素依存性脱水素酵素の機能・構造解析とその応用。
里村武範、川上竜巳、櫻庭春彦、大島敏久
- 生物工学会学会誌3月号、食品機能性成分としてのD-アミノ酸の可能性、大森勇門、大島敏久
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