大阪工業大学 工学部 生命工学科
分子生体機能学研究室
Molecular and Functional Biology Laboratory
Department of Biomedical Engineering, Osaka Institute of Technology

論文・総説 (英文)

・Hagihara H, Shoji H, Hattori S, Sala G, Takamiya Y, Tanaka M, Ihara M, Shibutani M, Hatada I, Hori K, Hoshino M, Nakao A, Mori Y, Okabe S, Matsushita M, Urbach A, Katayama Y, Matsumoto A, Nakayama KI, Katori S, Sato T, Iwasato T, Nakamura H, Goshima Y, Raveau M, Tatsukawa T, Yamakawa K, Takahashi N, Kasai H, Inazawa J, Nobuhisa I, Kagawa T, Taga T, Darwish M, Nishizono H, Takao K, Sapkota K, Nakazawa K, Takagi T, Fujisawa H, Sugimura Y, Yamanishi K, Rajagopal L, Hannah ND, Meltzer HY, Yamamoto T, Wakatsuki S, Araki T, Tabuchi K, Numakawa T, Kunugi H, Huang FL, Hayata-Takano A, Hashimoto H, Tamada K, Takumi T, Kasahara T, Kato T, Graef IA, Crabtree GR, Asaoka N, Hatakama H, Kaneko S, Kohno T, Hattori M, Hoshiba Y, Miyake R, Obi-Nagata K, Hayashi-Takagi A, Becker LJ, Yalcin I, Hagino Y, Kotajima-Murakami H, Moriya Y, Ikeda K, Kim H, Kaang BK, Otabi H, Yoshida Y, Toyoda A, Komiyama NH, Grant SGN, Ida-Eto M, Narita M, Matsumoto KI, Okuda-Ashitaka E, Ohmori I, Shimada T, Yamagata K, Ageta H, Tsuchida K, Inokuchi K, Sassa T, Kihara A, Fukasawa M, Usuda N, Katano T, Tanaka T, Yoshihara Y, Igarashi M, Hayashi T, Ishikawa K, Yamamoto S, Nishimura N, Nakada K, Hirotsune S, Egawa K, Higashisaka K, Tsutsumi Y, Nishihara S, Sugo N,
Yagi T, Ueno N, Yamamoto T, Kubo Y, Ohashi R, Shiina N, Shimizu K, Higo-Yamamoto S, Oishi K, Mori H, Furuse T, Tamura M, Shirakawa H, Sato DX, Inoue YU, Inoue T, Komine Y, Yamamori T, Sakimura K, Miyakawa T.
Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment.
eLife 12:RP89376, 2024.

・Kamada, H., Emura, K., Yamamoto, R., Kawahara, K.I., Uto, S., Minami, T., Ito, S., Matsumoto, K.-I. and Emiko Okuda-Ashitaka, E.
Hypersensitivity of myelinated A-fibers via toll-like receptor 5 promotes mechanical allodynia in tenascin-X-deficient mice associated with Ehlers-Danlos syndrome.
Sci. Rep. 13:18490, 2023.

・Okuda-Ashitaka, E. and Matsumoto, K.-I.
Tenascin-X as a causal gene for classical-like Ehlers-Danlos syndrome.
Front. Genet. 14:1107787, 2023 Review

・Nakatomi, K., Ueno, H., Ishikawa, Y., Salim, R.C., Mori, Y., Kanemoto, I., Tancharoen, S., Kikuchi, K., Miura, N., Omori, T., Okuda-Ashitaka, E., Matsumura, K., Imaizumi, H., Motomiya, Y., Maruyama, I. and Kawahara, K.I.
TLR4/MD-2 is a receptor for extracellular nucleophosmin 1.
Biomed. Rep. 14:21, 2021.

・Okuda-Ashitaka, E., Yuka Kakuchi, Y., Kakumoto, H., Yamanishi, S., Kamada, H., Yoshidu, T., Matsukawa, S., Ogura, N., Uto, S., Minami, T., Ito, S. and Matsumoto, K.-I.
Mechanical allodynia in mice with tenascin-X deficiency associated with Ehlers-Danlos syndrome.
Sci. Rep. 10:6569, 2020.

・Harada, M., Minami, T., Ito, S. and Okuda-Ashitaka, E.
Development of a novel photoaffinity probe for labeling nocistatin receptor.
Biochem. Biophys. Res. Commun., 501:514-519, 2018

・Kawabata, K., Nishimura, I., Fujiwara, T., Terauchi, S., Minami, T., Ito, S. and Okuda-Ashitaka, E.
Intrathecal administration of low-dose nociceptin/orphanin FQ induces allodynia via c-Jun N-terminal kinase and monocyte chemoattractant protein-1.
Eur. J. Neurosci., 43:1499-1508, 2016

・Okamoto, K., Ohashi, M., Ohno, K., Takeuchi, A., Matsuoka, E., Fujisato, K., Minami, T., Ito, S. and Okuda-Ashitaka, E.
Involvement of NIPSNAP1, a neuropeptide nocistatin-interacting protein, in inflammatory pain.
Mol. Pain, 12:1-11, 2016

・Okuda-Ashitaka, E. and Ito, S.
Pain regulation induced by nocistatin-targeting molecules: G protein-coupled-receptor and nocistatin-interacting protein.
Nociceptin Opioid (Litwack, G. eds)
Vitam. Horm., 97:147-165, 2015 Review

・Okuda-Ashitaka, E. and Ito, S.
Nocistain : milestone of one decade of research.
Molecular understanding of pain and future treatment of chronic pain. (Zhou, M. eds)
Curr. Pharm. Des., 21:868-884, 2015 Review

・Tsuda, M., Kaneko, S., Ando, A., Nishimura, T., Okuda-Ashitaka, E., Ito, S., Taomoto, M., Matsumura, M. and Takahashi, K.
Controllable urokinase gene expression in trabecular meshwork cells.
J. Clin. Exp. Ophthalmol. 5:329, 2014

・Okuda-Ashitaka, E., Minami, T., Tsubouchi, S., Kiyonari, H., Iwamatsu, A., Noda, T., Handa, H. and Ito, S.
Identification of NIPSNAP1 as a nocistatin-interacting protein involving pain transmission.
J. Biol. Chem., 287:10403-40413, 2012

・Kunori, S., Matsumura, S., Okuda-Ashitaka, E., Katano, T., Audoly, A.P., Urade, Y. and Ito, S.
A novel role of prostaglandin E2 in neuropathic pain: blockade of microglialmigration in the spinal cord.
Glia, 59:208-218, 2011

・Ohnaka, M., Okuda-Ashitaka, E., Kaneko, S., Ando, A., Maeda, M., Furuta, K., Suzuki, M., Takahashi, K. and Ito, S.
Induction of arginase II mRNA by nitric oxide using in vitro model of gyrate atrophy of choroid and retina.
Invest. Ophthalmol Vis. Sci., 52:1493-1500, 2011

・Matsumura, S., Kunori, S., Mabuchi, T., Katano, T., Nakazawa, T., Abe, T., Watanabe, M., Yamamoto, T., Okuda-Ashitaka, E. and Ito, S.
Impairment of CaMKII activation and attenuation of neuropathic pain in mice lacking NR2B phosphorylated at Tyr1472.
Eur. J. Neurosci., 32:798-810, 2010

・Matsumura, S., Takagi, K., Okuda-Ashitaka, E., Lu, J., Naritsuka, H., Yamaguchi, M. and Ito, S.
Characterization of nestin expression in the spinal cord of GFP transgenic mice after peripheral nerve injury.
Neuroscience, 170:942-953, 2010

・Lu, J., Katano, T., Okuda-Ashitaka, E., Oishi, Y., Urade, Y. and Ito, S.
Involvement of S-nitrosylation of actin in inhibition of neurotransmitter release by nitric oxide.
Mol. Pain, 5. 58-70, 2009

・Katano, T., Furue, H., Okuda-Ashitaka, E., Tagaya, M., Watanabe, M., Yoshimura, M. and Ito, S.
N-Ethylmaleimide-sensitive fusion protein (NSF) is involved in central sensitization in the spinal cord through GluR2 subunit composition switch after inflammation.
Eur. J. Neurosci., 27:3161-3170, 2008

・Takagi, K., Okuda-Ashitaka, E., Mabuchi, T., Katano, T., Ohnishi, T., Matsumura, S., Ohnaka, M., Kaneko, S., Abe, T., Hirata, T., Fujiwara, S., Minami, T. and Ito, S.
Involvement of stem cell factor and its receptor tyrosine kinase c-kit in pain regulation.
Neuroscience, 153:1278-1288, 2008

・Ohnishi, T., Okuda-Ashitaka, E., Matsumura, S., Katano, T., Nishizawa, M. and Ito, S.
Characterization of signaling pathway for the translocation of neuronal nitric oxide synthase to the plasma membrane by PACAP.
J. Neurochem., 105:2271-2285, 2008

・Moriuchi, H., Koda, N., Okuda-Ashitaka, E., Daiyasu, H., Ogasawara, K., Toh, H., Ito, S., Woodward, D.F. and Watanabe, K.
Molecular characterization of a novel type of prostamide/prostaglandin F synthase, belonging to the thioredoxin-like superfamily.
J. Biol. Chem., 283:792-801, 2008

・Xu, L., Mabuchi, T., Katano, T., Matsumura, S., Okuda-Ashitaka, E., Sakimura, K., Mishina, M. and Ito S.
Nitric oxide (NO) serves as a retrograde messenger to activate neuronal NO synthase in the spinal cord via NMDA receptors.
Nitric Oxide, 17:18-24, 2007

・Takagi, K., Matsumura, S., Okuda-Ashitaka, E., Okuda, K., Watanabe, J., Takahashi, H., Iwakura, Y. and Ito, S.
Interleukin-1 is not essential for expression of inducible NOS in hepatocytes induced by lipopolysaccharide in vivo.
Nitric Oxide, 16:433-441, 2007

・Kaneko, S., Okuda-Ashitaka, E., Ando, A., Nishimura, K., Igarashi, K., Maeda, M., Furuta, K., Suzuki, M., Matsumura, M. and Ito S.
Polyamines upregulate the mRNA expression of cationic amino acid transporter-1 in human retinal pigment epithelial cells.
Am. J. Physiol. Cell Physiol., 293:C729-737, 2007

・Xu, L., Okuda-Ashitaka, E., Matsumura, S., Mabuchi, T., Okamoto, S., Sakimura, K., Mishina, M. and Ito, S.
Signal pathways coupled to activation of neuronal nitric oxide synthase in the spinal cord by nociceptin/orphanin FQ.
Neuropharmacology, 52:1318-1325, 2007

・Kaneko, S., Ando, A., Okuda-Ashitaka, E., Maeda, M., Furuta, K., Suzuki, M., Matsumura, M. and Ito, S.
Ornithine transport via cationic amino acid transportor-1is involved in ornithine cytotoxicity in retinal pigment epithelial cells.
Invest. Ophthalmol Vis. Sci., 48:464-471, 2007

・Kaneko, S., Ueda-Yamada, M., Ando, A., Matsumura, S., Okuda-Ashitaka, E., Matsumura, M., Uyama, M. and Ito, S.
Cytotoxicity of spermine on retinal pigment epithelial cells.
Invest. Ophthalmol Vis. Sci., 48:455-463, 2007

・Katano, T., Mabuchi, T., Okuda-Ashitaka. E., Inagali, N., Kinumi, T. and Ito, S.
Proteomic identification of a novel isoform of collapsing response mediator protein-2 in spinal nerves peripheral to dorsal root ganglia.
Proteomics, 6:6085-6094, 2006

・Okuda-Ashitaka, E., Minami, T., Matsumura, S., Takeshima, H., Reinscheid, R. K., Civelli, O. and Ito, S.
The opioid peptide nociceptin/orphanin FQ mediates prostaglandin E2-induced allodynia, tactile pain associated with nerve injury.
Eur. J. Neurosci., 23:995-1004, 2006

・Matsumura, S., Abe, T., Mabuchi, T., Katano, T., Takagi, K., Okuda-Ashitaka, E., Tatumi, S., Nakai, Y., Sasaki, Y., Minami, T. and Ito, S.
Rho-kinase mediates spinal nitric oxide formation by prostaglandin E2 via EP3 subtype.
Biochem. Biophys. Res. Commun., 338:550-557, 2005

・Ando, A., Yamazaki, Y., Kaneko, S., Miyake, M., Nambu, R., Taomoto, M., Unezaki, S., Okuda-Ashitaka, E., Okumura, T., Ito, S. and Matsumura, M.
Cytoprotection by nipradiol, an anti-glaucomatous agent, via down-regulatoion of apoptosis related gene expression and activation of NF-kB.
Exp. Eye Res., 80:501-507, 2005

・Mabuchi, T., Shintani, N., Matsumura, S., Okuda-Ashitaka, E., Hashimoto, H., Muratani, T., Minami, T., Baba, A. and Ito, S.
Pituitary adenylate cyclase-activating polypeptide is required for the development of spinal sensitization and induction of neuropathic pain.
J. Neurosci., 24:7283-7291, 2004

・Unezaki, S., Nishizawa, M., Okuda-Ashitaka, E., Masu, Y., Mukai, M., Kobayashi, S., Sawamoto, K., Okano, H. and Ito, S.
Characterization of the isoforms of MOVO zinc finger protein, a mouse homologue of Drosophila Ovo, as transcription factor.
Gene, 336:47-58, 2004

・Otsuji, T., Okuda-Ashitaka, E., Kojima, S., Akiyama, H., Ito, S. and Ohmiya, Y.
Monitoring for dynamic biological processing by intra-molecular bioluminescence resonance energy transfer system using secreted luciferase.
Anal. Biochem., 329:230-2378, 2004

・Mabuchi,T., Matsumura, S., Okuda-Ashitaka, E., Kitano, T., Kojima, H., Nagano, T.,Minami, T. and Ito, S.
Attenuation of neuropathic pain by nociceptin/orphanin FQ antagonist JTC-801 is mediated by inhibition of nitric oxide production.
Eur. J. Neurosci., 17:1384-1392, 2003

・Zeilhofofer, H. U., Reinscheid, R. K., and Okuda-Ashitaka, E.
Nociceptin, Nocistatin and Pain.
Proceeding of the 10th World Congress on Pain, Progress in Pain Reserch and Management, 24:469-480
(in Jonathan O.Dostrovsky, Daniel B. Carr, and Martin Koltzenburg) IASP Press, Seattle, 2003

・Muratani, T., Minami, T., Enomoto, U., Sakai, M., Okuda-Ashitaka, E., Kiyokane, K., Mori, H. and Ito, S.
Characterization of nociceptin/orphanin FQ-induced pain responses by the novel receptor antagonist JTC-801.
J. Pharmacol. Exp. Ther., 303:424-430, 2002

・Okuda-Ashitaka, E., Minami, T. and Ito, S.
Pain transmission regulated by novel neuropeptides nocistatin and nociceptin/orphanin FQ.
J. Biol. Macromol., 2:3-10, 2002 Review

・Minami, T., Matsumura, S., Okuda-Ashitaka, E., Shimamoto, K., Sakimura, K., Mishina, M., Mori, H. and Ito, S.
Characterization of the glutamatergic system for induction and maintenance of allodynia.
Brain Res., 895:178-185, 2001

・Ito, S., Okuda-Ashitaka, E. and Minam, T.
Central and peripheral roles of prostaglandins in pain and their interactions with novel neuropeptides nociceptin and nocistatin.
Neurosci. Res., 41:299-332, 2001 Review

・Minam, T., Okuda-Ashitaka, E., Mori, H., Sakimura, K., Watanabe, M., Mishina, M. and Ito, S.
Characterization of nociceptin/orphanin FQ-induced pain responses in conscious mice: neonatal capsaicin treatment and NMDA receptor e subunit knockout mice.
Neuroscience, 97:133-142, 2000

・Nakano, H., Minami, T., Abe, K., Arai, T., Tokumura, M., Ibii, N., Okuda-Ashitaka, E., Mori, H. and Ito, S.
Effect of intrathecal nocistatin on the formalin-induced pain in mice versus that of nociceptin/orphanin FQ.
J. Pharmacol. Exp. Ther., 292:331-336, 2000

・Okuda-Ashitaka, E. and Ito, S.
Nocistatin: a novel neuropeptide encoded by the gene for the nociceptin/orphanin FQ precursor.
Peptides, 21:1101-1109, 2000 Review

・Suzuki-Yamamoto, T., Nishizawa, M., Fukui, M., Okuda-Ashitaka, E., Nakajima, T., Ito, S. and Watanabe, K.
cDNA cloning, expression and charcterization of human prostaglandin F synthase.
FEBS lett., 462:355-340, 1999

・Ikeda, S., Okuda-Ashitaka, E., Masu, Y., Suzuki, T., Watanabe, K., Nakao, M., Shingu, K. and Ito, S.
Cloning and characterization of two novel aldo-keto reductases (AKR1C12 and AKR1C13) from mouse stomach.
FEBS lett., 459:433-437, 1999

・Minami, T., Okuda-Ashitaka, E., Hori, Y., Sakuma, S., Sugimoto, T., Sakimura, K., Mishina, M. and Ito, S.
Involvement of primary afferent C-fibres in touch-evoked pain (allodynia) induced by prostaglandin E2.
Eur. J. Neurosci., 11:1849-1856, 1999

・Lee, T-L., Fung, F. M. Y., Chen, F-G., Chou, N., Okuda-Ashitaka, E., Ito, S., Nishiuchi, Y., Kimura, T. and Tachibana, S.
Identification of human, rat and mouse nocistatin in brain and human cerebrospinal fluid.
NeuroReport, 10:1537-1341, 1999

・Okuda-Ashitaka, E., Minami. T., Tachibana, S., Yoshihara, Y., Nishiuchi,Y., Kimura,T. and Ito, S.
Strucutre-activity relationships of nocistatin: a novel peptide blocking nociceptin-induced hyperalgesia and allodynia.
Peptide 1998, Proceeding of the 25th European Peptide Symposium, pp.736-737, (in Bajusz, S. and Hudecz, F. eds) Akademiai Kiado, Budapest,1999

・Okuda-Ashitaka, E., Minami. T., Tachibana, S., Yoshihara, Y., Nishiuchi,Y., Kimura,T. and Ito, S.
Strucutre-activity relationships of nocistatin: a novel peptide blocking nociceptin action in pain transmission.
Peptide science 1998, Proceeding of the 35th Japan Peptide Symposium, pp.209-212 (in Kondo, M. ed)
Protein Research Foundation, Osaka, 1999

・Nicol, B., Lambert, D. G., Rowbotham, D. J., Okuda-Ashitaka, E., Ito, S., Smart, D. and McKnight, A. T.
Nocistatin reverses nociceptin inhibition of glutamate release from rat brain slices.
Eur. J. Pharmacol., 356:R1-R3, 1998

・Minami, T., Okuda-Ashitaka, E., Nishiuchi, Y., Kimura, T., Tachibana, S., Mori, H. and Ito, S.
Anti-nociceptive responses produced by human putative counterpart of nocistatin.
Br. J. Pharmacol., 124:1016-1018, 1998

・Masu, Y., Ikeda, S., Okuda-Ashitaka, E., Sato, E. and Ito, S.
Expression of murine novel zinc finger proteins highly homologous to Drosophila ovo gene product in testis.
FEBS lett., 421:224-228, 1998

・Okuda-Ashitaka, E., Minami, T., Tachibana, S., Yoshihara, Y., Nishiuchi, Y., Kimura, T. and Ito, S.
Nocistatin, a peptide that blocks nociceptin action in pain transmission.
Nature, 392:286-289, 1998

・Minami, T., Okuda-Ashitaka, E., Nishizawa, M., Mori, H. and Ito, S.
Inhibition of nociceptin-induced allodynia in conscious mice by prostaglandin D2.
Br. J. Pharmacol., 122:605-610, 1997

・Hara,N., Minami, T., Okuda-Ashitaka, E., Sugimoto, T., Sakai, M., Onaka, M., Mori, H., Imanishi, T., Shingu, K. and Ito, S.
Characterization of nociceptin, a novel opioid peptide, for pain transmission in conscious mice.
Br. J. Pharmacol., 121:401-408, 1997

・Ezashi, T., Sakamoto, K., Miwa, K., Okuda-Ashitaka, E., Ito, S. and Hayaishi, O.
Genomic organization and characterization of the bovine prostaglandin F2aαreceptor gene.
Gene, 190:271-278, 1997

・Okuda-Ashitaka, E., Tachibana, S., Houtani, T., Minami, T., Masu, Y., Nishi, M., Takeshima, H., Sugimoto, T. and Ito, S.
Identification and characterization of an endogenous ligand for opioid receptor homologue ROR-C: its involvement in allodynic response to innocuous stimulus.
Mol. Brain. Res., 43:96-104, 1996

・Minami, T., Okuda-Ashitaka, E., Mori, H., Ito, S. and Hayaishi, O. 
Prostaglandin D2 inhibits prostaglandin E2-induced allodynia in conscious mice. 
J. Pharmacol. Exp. Ther., 278:1146-1152, 1996

・Okuda-Ashitaka, E., Sakamoto, K., Ezashi, T., Miwa K., Ito, S. and Hayaishi, O. 
Suppression of prostaglandin E receptor signaling by the variant form of EP1 subtype. 
J.Biol. Chem., 271:31255-31261, 1996

・Minami, T., Onaka, M., Mori, H., Okuda-Ashitaka, E., Ito, S. and Hayaishi, O. 
L-NAME, an inhibitor of nitric oxide synthase, blocks the established allodynia induced by intrathecal administration of prostaglandin E2. 
Neurosci. Lett., 201:239-242, 1995

・Sakamoto, K., Ezashi, T., Miwa, K., Okuda-Ashitaka, E., Houtani, T., Sugimoto, T., Ito, S. and Hayaishi, O.
Molecular cloning and expression of a cDNA of the bovine prostaglandin F2α receptor.
Advances in Prostaglandin, Thromboxane, Leukotriene Res. 23:259-261, 1995

・Sakamoto, K., Miwa, K., Ezashi, T., Okuda-Ashitaka, E., Okuda, K., Houtani, T., Sugimoto, T., Ito, S. and Hayaishi, O.
Expression of mRNA encoding the prostaglandin F2a receptor in the bovine corpora lutea throughout the oestrous cycle and pregnancy.
J. Reprod. Fertil., 103:99-105, 1994

・Ito, S., Sakamoto, K., Mochizuki-Oda, N., Ezashi, T., Miwa, K., Okuda-Ashitaka, E., Shevchenko, V. I., Kiso, Y. and Hayaishi, O. Prostaglandin F2a receptor is coupled to Gq in cDNA-transfected Chinese hamster ovary cells.
Biochem. Biophys. Res. Commun., 200:756-762, 1994

・Sakamoto, K., Ezashi, T., Miwa, K., Okuda-Ashitaka, E., Houtani, T., Sugimoto, T., Ito, S. and Hayaishi, O.
Molecular cloning and expression of a cDNA of the bovine prostaglandin F2a receptor.
J. Biol. Chem., 269:3881-3856, 1994

・Okuda-Ashitaka, E., Sakamoto, K., Giles, H., Ito, S. and Hayaishi, O.
Cyclic-AMP-dependent Ca2+ influx elicited by prostaglandin D2 in freshly isolated nonchromaffin cells from bovine adrenal medulla.
Biochim. Biophys. Acta., 1176:148-154, 1993

・Oda, K., Fujitani, F., Watanabe, T., Inui, T., Okada, T., Urade, Y.,Okuda-Ashitaka, E. and Ito, S.
Endothelin stimulates both cAMP formation and phosphatidylinositol hydrolysis in cultured embryonic bovine tracheal cells.
FEBS Lett., 299:187-191, 1992

・Ito, S., Negishi, M., Sugama, K., Okuda-Ashitaka, E. and Hayaishi, O.
Signal transduction coupled to prostaglandin D2.
Advances in Prostaglandin, Thromboxane, Leukotriene Res. 21:71-74, 1990

・Okuda-Ashitaka, E., Negishi, M., Sugama, K., Hatanaka, M. and Ito, S.
Cyclic AMP-mediated inhibition of cell growth by prostaglandin D2 in a fibroblastic cell line (EBTr).
Eicosanoids, 3: 213-218, 1990

・Ito, S., Okuda, E., Sugama, K., Negishi, M. and Hayaishi, O. 
Evaluation of ZK110841 and AH6809, an agonist and an antagnist of prostaglandin DP-receptors on human platelets, with a PGD2-responsive cell line from bovine embryonic trachea. 
Br. J. Pharmacol., 99:13-14, 1990

総説・著書(和文)

・近江谷克裕, 芦高恵美子, 吉宗一晃
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糖尿病性神経因性疼痛の分子メカニズム
Bio Clinica 32:75-77, 2017

・芦高恵美子, 伊藤誠二.
III. 各種疾患 11.機能性疾患 1)ノシセプチンとノシスタチン.
Annual Review 神経 2014, 272-279, 2014 中外医学社

・芦高恵美子, 伊藤誠二.
神経ペプチドUpdate  痛み ノシセプチンとノシスタチン.
Clinical Neuroscience 30:148-151, 2012

・芦高恵美子.
脊髄の疼痛発症におけるシナプス制御.
生化学 84:1019-1023, 2012

・芦高恵美子.
アロディニア.
生化学 84:1031, 2012

・芦高恵美子.
第3章 その他の慢性疼痛のメカニズムと治療のアプローチ  第1節 遺伝子的要因による痛み発現メカニズム.
慢性疼痛における薬剤選定と治療薬開発 124-130, 2010, 技術情報協会

・松村伸治, 阿部哲也, 芦高恵美子, 伊藤誠二.
痛みのメカニズムとその制御、痛みにおけるNOの関与.
Bio Clinica 23:397-403, 2008

・芦高恵美子, 阿部哲也, 松村伸治, 伊藤誠二.
脊髄後角におけるNMDA受容体リン酸化と神経因性疼痛.
慢性疼痛、vol.26、pp.41-47、2007

・南敏明, 芦高恵美子, 伊藤誠二.
プロスタグランジンとノシセプチン.
麻酔 56:S172-S178, 2007.

・芦高恵美子, 南敏明, 伊藤誠二.
脊髄におけるノシセプチン/オーファニンFQを介したプロスタグランジンによる疼痛制御ネットワーク.
ペインクリニック 27:547-559, 2006

・芦高恵美子, 伊藤誠二
痛みシグナルの制御機構と最新治療エビデンス -ノシセプチンの疼痛制御-
医学のあゆみ 211:375-379, 2004

・芦高恵美子, 伊藤誠二
ノシセプチン
痛み -基礎・診断・治療- (編集 花岡一雄), 37-40, 2003, 朝倉書店

・伊藤誠二, 芦高恵美子, 南敏明.
ノシセプチンとノシスタチンの痛覚調節機構.
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・南敏明, 中野弘行, 芦高恵美子, 森秀磨, 伊藤誠二.
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